Now in its ninth year, the Comprehensive Care Sustainability Collaborative (CCSC) initiative was founded to support the sustainability of the integrated comprehensive model of care. CCSC has sought to achieve this aim by facilitating value-based dialogue and payer/provider collaboration. A collaborative working relationship and mutual understanding among all stakeholders is needed now more than ever considering a rapidly changing therapeutic landscape. This session, held at the National Hemophilia Foundation’s Bleeding Disorders Conference on August 25, 2022, includes a faculty panel offering diverse perspectives and engaging in a robust dialogue with the goal of increased collaboration as the promise of innovative therapies bring new challenges and opportunities. Visit CCSChemo.com for more information.