Oct 6, 2022

Tell us a little bit about yourself!

I’m Dr. Jyoti Mathur. From 2007 to 2009, I was a fellow with the Judith Graham Pool Postdoctoral Research Fellowship. When I was selected for the fellowship, I was a postdoctoral fellow at Stanford Medical School.

What did your research focus on?

My work was titled “Proficient AAV Vectors for the Treatment of Hemophilia B,” and it sought out to create a new, more stabilized double-stranded AAV-based viral vectors in order to find more efficient treatments for hemophilia B.

How did the JGP Fellowship support your research at the time? Does it continue to influence your work now?

The JGP fellowship supported some ground-breaking work on design and validation of new stabilized, double-stranded AAV-based viral vectors with chimeric capsids for efficient delivery of human Factor IX for treatment of Hemophilia B.  While I no longer study blood clotting disorders, my research has come full circle as I now work in cell therapy and gene-edited human T cells for treatment of solid tumors.

How did you hear about the JGP Fellowship?

My advisor, Dr. Mark Kay, told me about the program. It was also in Dr. Kay’s Gene Therapy lab that I was able to conduct this research.

Beyond your initial study, how has the JGP fellowship impacted your career?

The NHF fellowship was instrumental in securing a position at Stanford and my training and connections there have opened many doors especially as I boot strapped my own company and explored venture capital industry.

The Judith Graham Pool Postdoctoral Research Fellowship has been supporting basic science and pre-clinical research to expand our understanding of bleeding disorders since 1972. Learn more here.