NBDF funds a broad range of research programs that seek to increase our understanding of the science behind bleeding disorders, how they affect people's lives, and pathways to better treatments and cures.
Structure of Factor VIII’s C Domains and their Epitopes
Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Hemophilia A (Factor VIII/F8)
Platelet Mechanism Regulating Thrombin Generation
Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Platelets
Per Dr. Kempton, the JGP assisted her in determining the direction of her future research. As a result of her JGP project, Dr. Kempton was published in ATVB and published several abstracts.
Nonviral Gene Delivery for Hemophilia
Year:
-
Grants:
Career Development Award
Gene Therapy
Hemophilia A (Factor VIII/F8)
Hemophilia B (Factor IX/F9)
Development of a Novel Genomic Transfer Approach for the Treatment of Hemophilia Based on Transduction of Adipose Tissue Using Replication-Defective HSV-1 Vectors
Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Gene Therapy
Hemophilia A (Factor VIII/F8)
Hemophilia B (Factor IX/F9)
Exploiting Mouse Models to Elucidate the Cellular and Molecular Mechanisms Involved in the Pathogenesis of Platelet Storage Pool Deficiencies
Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Platelets
Gene Therapy for Hemophilia B by Direct Intramuscular Injections of Recombinant Adeno Associated Virus Serotype Vectors
Year:
-
Grants:
Career Development Award
Gene Therapy
Hemophilia B (Factor IX/F9)
Identification of Complement-Type Repeats of LRP Responsible for Interaction with A2 Domain of Factor VIII
Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Hemophilia A (Factor VIII/F8)
Non-primate Lentiviral Vector-Based Gene Therapy for Hemophilia A
Year:
-
Grants:
Career Development Award
Gene Therapy
Hemophilia A (Factor VIII/F8)
Function of Coagulation Factor V in Plasma and Platelet Pools
Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Platelets
Study of Interactive Sites of Factor VIIIa with Factor IXa
Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Hemophilia A (Factor VIII/F8)
Hemophilia B (Factor IX/F9)
Immunology of Liver-Derived Expression of Factor IX from AAV Vectors
Year:
-
Grants:
Career Development Award
Hemophilia B (Factor IX/F9)
Gene Therapy
Development of Improved Adenoviral Vectors Lacking All Adenoviral Coding Sequences for Hemophilia Gene Therapy
Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Gene Therapy
Hemophilia A (Factor VIII/F8)
Hemophilia B (Factor IX/F9)
Correction of Hemophilia with Lentiviral Vectors
Year:
-
Grants:
Career Development Award
Hemophilia A (Factor VIII/F8)
Hemophilia B (Factor IX/F9)
Gene Therapy
Molecular Mechanisms of Combined Factors V and VIII Deficiency
Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Factor V
Hemophilia A (Factor VIII/F8)
Development and Characterization of Novel Genetically Engineered Factor VIII Molecules with Increased Activity and Stability
Year:
-
Grants:
Career Development Award
Hemophilia A (Factor VIII/F8)
Correction of Factor VIII Deficiency by Nonprimate Lentivirus-Based Gene Therapy
Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Gene Therapy
Hemophilia A (Factor VIII/F8)
Treatment of a Mouse Model of Hemophilia Using AAV Vectors Expressing Murine Factor VIII
Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Hemophilia A (Factor VIII/F8)
Gene Therapy
Retroviral Vector-Mediated Gene Therapy for Canine Hemophilia B
Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Gene Therapy
Hemophilia B (Factor IX/F9)
Mechanisms Involved in Transduction of Human Lentivirus in Liver: A Strategy for Hemophilia Gene Therapy
Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Gene Therapy
Hemophilia A (Factor VIII/F8)
Hemophilia B (Factor IX/F9)
Vascular Bed-Specific Regulation of the VWF Gene
Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Von Willebrand Disease