NBDF funds a broad range of research programs that seek to increase our understanding of the science behind bleeding disorders, how they affect people's lives, and pathways to better treatments and cures.

Structure of Factor VIII’s C Domains and their Epitopes

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Hemophilia A (Factor VIII/F8)
Author(s):
Ting-Chang Hsu
Christine_Kempton

Platelet Mechanism Regulating Thrombin Generation

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Platelets
Author(s):
Christine L. Kempton

Per Dr. Kempton, the JGP assisted her in determining the direction of her future research. As a result of her JGP project, Dr. Kempton was published in ATVB and published several abstracts.

Nonviral Gene Delivery for Hemophilia

Year:
-
Grants:
Career Development Award
Gene Therapy
Hemophilia A (Factor VIII/F8)
Hemophilia B (Factor IX/F9)
Author(s):
Carol H. Miao

Development of a Novel Genomic Transfer Approach for the Treatment of Hemophilia Based on Transduction of Adipose Tissue Using Replication-Defective HSV-1 Vectors

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Gene Therapy
Hemophilia A (Factor VIII/F8)
Hemophilia B (Factor IX/F9)
Author(s):
Julie Fradette

Exploiting Mouse Models to Elucidate the Cellular and Molecular Mechanisms Involved in the Pathogenesis of Platelet Storage Pool Deficiencies

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Platelets
Author(s):
Lisa S. Webb

Gene Therapy for Hemophilia B by Direct Intramuscular Injections of Recombinant Adeno Associated Virus Serotype Vectors

Year:
-
Grants:
Career Development Award
Gene Therapy
Hemophilia B (Factor IX/F9)
Author(s):
Hengjun Chao

Identification of Complement-Type Repeats of LRP Responsible for Interaction with A2 Domain of Factor VIII

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Hemophilia A (Factor VIII/F8)
Author(s):
Andrey Garunovich Sarafanov

Non-primate Lentiviral Vector-Based Gene Therapy for Hemophilia A

Year:
-
Grants:
Career Development Award
Gene Therapy
Hemophilia A (Factor VIII/F8)
Author(s):
Yubin Kang

Function of Coagulation Factor V in Plasma and Platelet Pools

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Platelets
Author(s):
Hongmin Sun

Study of Interactive Sites of Factor VIIIa with Factor IXa

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Hemophilia A (Factor VIII/F8)
Hemophilia B (Factor IX/F9)
Author(s):
Peter Vincent Jenkins
Roland Herzog

Immunology of Liver-Derived Expression of Factor IX from AAV Vectors

Year:
-
Grants:
Career Development Award
Hemophilia B (Factor IX/F9)
Gene Therapy
Author(s):
Roland W. Herzog
Anja_Ehrhardt

Development of Improved Adenoviral Vectors Lacking All Adenoviral Coding Sequences for Hemophilia Gene Therapy

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Gene Therapy
Hemophilia A (Factor VIII/F8)
Hemophilia B (Factor IX/F9)
Author(s):
Anja Ehrardt

Correction of Hemophilia with Lentiviral Vectors

Year:
-
Grants:
Career Development Award
Hemophilia A (Factor VIII/F8)
Hemophilia B (Factor IX/F9)
Gene Therapy
Author(s):
Tal Kafri

Molecular Mechanisms of Combined Factors V and VIII Deficiency

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Factor V
Hemophilia A (Factor VIII/F8)
Author(s):
Bin Zhang
Steven Pipe

Development and Characterization of Novel Genetically Engineered Factor VIII Molecules with Increased Activity and Stability

Year:
-
Grants:
Career Development Award
Hemophilia A (Factor VIII/F8)
Author(s):
Steven Wesley Pipe

Correction of Factor VIII Deficiency by Nonprimate Lentivirus-Based Gene Therapy

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Gene Therapy
Hemophilia A (Factor VIII/F8)
Author(s):
Yubin Kang

Treatment of a Mouse Model of Hemophilia Using AAV Vectors Expressing Murine Factor VIII

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Hemophilia A (Factor VIII/F8)
Gene Therapy
Author(s):
Cathryn Sanghae Mah

Retroviral Vector-Mediated Gene Therapy for Canine Hemophilia B

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Gene Therapy
Hemophilia B (Factor IX/F9)
Author(s):
Lingfei Xu

Mechanisms Involved in Transduction of Human Lentivirus in Liver: A Strategy for Hemophilia Gene Therapy

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Gene Therapy
Hemophilia A (Factor VIII/F8)
Hemophilia B (Factor IX/F9)
Author(s):
Frank Park

Vascular Bed-Specific Regulation of the VWF Gene

Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Von Willebrand Disease
Author(s):
Jo Chao Tsai