NBDF funds a broad range of research programs that seek to increase our understanding of the science behind bleeding disorders, how they affect people's lives, and pathways to better treatments and cures.
AAV Hemophilia Gene Therapy Vectors
Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Gene Therapy
Hemophilia A (Factor VIII/F8)
Hemophilia B (Factor IX/F9)
Impact of VWF on Factor VIII Gene Targeting
Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Von Willebrand Disease
Hemophilia A (Factor VIII/F8)
Induction of Immune Tolerance to Factor IX
Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Hemophilia B (Factor IX/F9)
Inhibitors
Vitamin K-Dependent Carboxylase (1997)
Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Vitamin K
Factor VIII Delivery via Skin
Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Hemophilia A (Factor VIII/F8)
Vitamin K-Dependent Carboxylase (1996)
Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Vitamin K
Interaction of Factor VIII with Factor IXa
Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Hemophilia A (Factor VIII/F8)
Hemophilia B (Factor IX/F9)
Persistent Expression of Factor IX
Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Hemophilia B (Factor IX/F9)
HIV Resistance in Hemophiliacs
Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
HIV/AIDS
Hemophilia A (Factor VIII/F8)
Hemophilia B (Factor IX/F9)
Per Dr. Tenenbaum, the JGP provided him with the necessary framework to complete his Postdoctoral Fellowship at Duke University Medical Center and his first academic position at SUNY, where he is currently a Professor specializing in RNA Nanotechnology and Genomics. Although he has not remained in the field of hematology, his current research does intersect with many diseases, including those in the field of hematology (and specifically, hemophilia). The intersection is in relation to gene therapy technology that he is developing.
Factor VIII Gene Therapy Vectors
Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Gene Therapy
Hemophilia A (Factor VIII/F8)
Gene Therapy for Hemophilia B
Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Gene Therapy
Hemophilia B (Factor IX/F9)
Factor VIII–Specific T Lymphocytes
Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Hemophilia A (Factor VIII/F8)
HIV/AIDS
Per Dr. Singer, the JGP greatly influenced her career in research. It allowed her to focus on a research project, understand the process of asking a question/creating a hypothesis and developing (with guidance) a research plan; as well as analyze the date, present it (at NHG meeting at ASH) and write/publish it. It sparked her interest in hematology and in clinical research. She has pursued her work in the field of Pediatric Hematology and has obtained funding for research (including a K23 award). She has continued with ‘benign hematology’, focusing on Thalassemia (clinical and clinical research), as well as general hematology and hemostasis. Recently, she has become more involved in hemostasis (clinical care and sponsored studies related to bleeding/thrombosis).
Vitamin K-Dependent Carboxylase (1991)
Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Vitamin K
Gene Therapy of Hemophilia B
Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Gene Therapy
Hemophilia A (Factor VIII/F8)
Hemophilia B (Factor IX/F9)
Genetics of Type I/ III von Willebrand Disease
Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Von Willebrand Disease
Gene Therapy for Hemophilia A and B
Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Gene Therapy
Hemophilia A (Factor VIII/F8)
Hemophilia B (Factor IX/F9)
Carbohydrate and Carbohydrate Sulfation in the Structure and Function of von Willebrand Factor
Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Von Willebrand Disease
Replacement of the Factor IX Gene in a Canine Hemophilia B Model
Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Hemophilia B (Factor IX/F9)
Gene Therapy
Molecular and Cell Biology on von Willebrand Factor Variants
Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Von Willebrand Disease
The Molecular Biology of Canine Hemophilia B
Year:
-
Grants:
Judith Graham Pool Postdoctoral Research Fellowship
Hemophilia B (Factor IX/F9)