Hepatitis B vaccination is introduced in the U.S.

Cloning of factor IX is first reported.

NHF agrees to work with CDC, FDA, and NIH to establish surveillance system of hemophiliacs with symptoms of opportunistic infections

On July 16, 1982, NHF was alerted by the Centers for Disease Control that three people with hemophilia had come down with the newly defined immune-deficiency syndrome. When the NHF began to investigate, however, the organization's leaders decided that the risk for hemophiliacs from not using the blood concentrate was far greater than the risk posed by this new disease, which seemed to be affecting very few people.

The CDC reports the first AIDS cases in people with hemophilia through the use of tainted blood products used to treat bleeding disorders.

The CDC reports the first cases of AIDS in the USA.

In 1980, Hemophilia of Michigan works with state legislators to extend specialized healthcare coverage provided by Michigan’s Children’s Special Healthcare Services (CSHCS) to adults as well as children with bleeding disorders.

Thanks to NHF advocates, the Wisconsin Hemophilia Home Care Bill becomes law.

It is discovered that desmopressin acetate (DDAVP) could boost levels of both factor VIII (8) and von Willebrand factor (vWF). DDAVP remains a useful option in mild forms of these conditions.

NHF is accredited by the Combined Federal Campaign.